Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455802 | 0.90 | ALDH1A1 (0.42) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL23656658 | 0.88 | MEN1 (0.39) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21455436 | 0.85 | MEN1 (0.37) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL23229153 | 0.83 | TBXAS1 (0.48) | TBXAS1PKMTDP1 | |
| SCHEMBL23229180 | 0.83 | TBXAS1 (0.43) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL18642486 | 0.83 | DPP4 (0.46) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21456024 | 0.81 | DPP4 (0.41) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL23656748 | 0.80 | MEN1 (0.34) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL21455827 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2ANPSR1POLBHPGD | |
| SCHEMBL23850649 | 0.79 | MEN1 (0.41) | MEN1KMT2ANPSR1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |