Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.34 |
| ▸ | FNTB | P49356 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | USP14 | P54578 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21455591 | 0.85 | ALDH1A1 (0.40) | PDCD1CD274TRPV4FNTAFNTB | |
| SCHEMBL21455476 | 0.84 | MAPT (0.35) | TBXAS1GAANPSR1CYP1A2SMN1; SMN2 | |
| SCHEMBL21455194 | 0.82 | TBXAS1 (0.45) | TBXAS1NPSR1SMN1; SMN2ALDH1A1PKM | |
| SCHEMBL24200327 | 0.79 | PDCD1 (0.36) | PDCD1CD274TRPV4FNTAFNTB | |
| SCHEMBL16109213 | 0.79 | DPP4 (0.43) | PDCD1CD274TRPV4SMN1; SMN2ALDH1A1 | |
| SCHEMBL21455523 | 0.78 | ALDH1A1 (0.37) | TBXAS1NPSR1CYP1A2ALDH1A1LMNA | |
| SCHEMBL23241807 | 0.76 | PDCD1 (0.34) | PDCD1CD274TRPV4ALOX15ALDH1A1 | |
| SCHEMBL23832289 | 0.74 | PDCD1 (0.45) | PDCD1CD274ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL30154496 | 0.74 | PDCD1 (0.45) | PDCD1CD274ALOX15SMN1; SMN2ALDH1A1 | |
| SCHEMBL30088492 | 0.74 | PDCD1 (0.45) | PDCD1CD274ALOX15ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |