Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18642529 | 0.80 | EGFR (0.47) | ALDH1A1TDP1MAPTLMNAXBP1 | |
| SCHEMBL29853015 | 0.80 | EGFR (0.47) | ALDH1A1TDP1MAPTLMNAXBP1 | |
| SCHEMBL10653936 | 0.78 | MAPT (0.49) | ALDH1A1TDP1MAPTLMNAMAPK1 | |
| SCHEMBL23616906 | 0.77 | AKR1B1 (0.47) | CA9CA14ALDH1A1MAPTTSHR | |
| SCHEMBL10651962 | 0.75 | MAPT (0.46) | ALDH1A1TDP1MAPTLMNAMAPK1 | |
| SCHEMBL2035801 | 0.75 | CA12 (0.40) | CA9CA14TDP1MAPTTSHR | |
| SCHEMBL2031959 | 0.72 | CYP3A4 (0.42) | CA9CA14ALDH1A1TDP1MAPT | |
| SCHEMBL23617085 | 0.72 | AKR1A1 (0.30) | — | |
| SCHEMBL3849718 | 0.72 | CA3 (0.52) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL23464576 | 0.69 | CA3 (0.41) | CA3CA6CA5ACA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3687506-B1 | SUBSTITUTED BENZOFURAN, BENZOPYRROLE, BENZOTHIOPHENE, AND STRUCTURALLY RELATED COMPLEMENT INHIBITORS | BIOCRYST PHARM INC (US) | 2021-07-07 | — | — | EP | disclosed |