SCHEMBL23617652

SCHEMBL23617652

CNS(=O)(=O)N(C)CCN(C)C

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
PRMT3 O60678 1/20 0.36
CARM1 Q86X55 1/20 0.36
PRMT6 Q96LA8 1/20 0.36
PRMT1 Q99873 1/20 0.36
PRMT8 Q9NR22 1/20 0.36
CA12 O43570 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23617445 0.75 CA1 (0.31) ALDH1A1CA2
SCHEMBL23617843 0.74
SCHEMBL23617444 0.72 GSTO1 (0.36)
SCHEMBL18599578 0.72 ALDH1A1 (0.30) ALDH1A1
SCHEMBL48410 0.70 MEN1 (0.42) ALDH1A1CA12CA2CA3CA4
SCHEMBL1487364 0.69 CA12 (0.40) ALDH1A1CA12CA2CA3CA4
SCHEMBL3760967 0.67
SCHEMBL1487363 0.67 ALDH1A1 (0.39) ALDH1A1PRMT3CARM1PRMT6PRMT1
Hydrochloric Acid SCHEMBL2070490 0.67 CA12 (0.36) ALDH1A1CA12CA2CA3CA4
SCHEMBL41866 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3589630-B1 CYCLIC SULFAMIDE COMPOUNDS AND METHODS OF USING SAME ASSEMBLY BIOSCIENCES INC (US) 2021-07-07 EP disclosed