Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619030 | 0.93 | RORC (0.41) | RORCPDE2A | |
| SCHEMBL19864427 | 0.93 | MAPK1 (0.38) | RORCPDE2A | |
| SCHEMBL23618978 | 0.88 | PDE2A (0.37) | PDE2A | |
| SCHEMBL23619077 | 0.86 | MAPK1 (0.41) | RORCPDE2A | |
| SCHEMBL28614477 | 0.84 | RORC (0.48) | RORC | |
| SCHEMBL23619019 | 0.84 | RORC (0.48) | RORC | |
| SCHEMBL19864490 | 0.81 | PDE2A (0.37) | PDE2A | |
| SCHEMBL19864656 | 0.80 | MAPK1 (0.39) | PDE2A | |
| SCHEMBL23619076 | 0.80 | PDE2A (0.34) | PDE2A | |
| SCHEMBL23611042 | 0.79 | RORC (0.46) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136339-A1 | AMIDE COMPOUND WITH BICYCLIC STRUCTURE AND USE THEREOF IN DRUG | 广东东阳光药业有限公司 | 2021-07-08 | — | — | WO | disclosed |