Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28614477 | 1.00 | RORC (0.48) | RORCMAPK1 | |
| SCHEMBL23618977 | 0.92 | GAA (0.42) | RORC | |
| SCHEMBL28615402 | 0.92 | GAA (0.42) | RORC | |
| SCHEMBL23611042 | 0.91 | RORC (0.46) | RORC | |
| SCHEMBL23611040 | 0.91 | RORC (0.46) | RORC | |
| SCHEMBL28621548 | 0.91 | RORC (0.40) | RORC | |
| SCHEMBL23619029 | 0.91 | RORC (0.40) | RORC | |
| SCHEMBL23619001 | 0.89 | SMN1; SMN2 (0.40) | RORC | |
| SCHEMBL23619004 | 0.85 | RORC (0.49) | RORC | |
| SCHEMBL23618976 | 0.84 | RORC (0.42) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121463-A | Amide compound with bicyclic structure and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-16 | — | — | CN | disclosed |
| WO-2021136339-A1 | AMIDE COMPOUND WITH BICYCLIC STRUCTURE AND USE THEREOF IN DRUG | 广东东阳光药业有限公司 | 2021-07-08 | — | — | WO | disclosed |