Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 5/20 | 0.44 |
| ▸ | ANO1 | Q5XXA6 | 8/20 | 0.41 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.39 |
| ▸ | RORA | P35398 | 1/20 | 0.39 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24714040 | 0.86 | RORA (0.44) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619949 | 0.85 | ANO1 (0.47) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619970 | 0.83 | ANO1 (0.44) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619738 | 0.83 | KCNJ5 (0.48) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23620005 | 0.83 | P2RX4 (0.49) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23620020 | 0.82 | KCNJ5 (0.53) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23620183 | 0.82 | ANO1 (0.45) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23620187 | 0.82 | ANO1 (0.43) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23619947 | 0.82 | P2RX4 (0.47) | P2RX4ANO1KCNJ5KCNJ3RORA | |
| SCHEMBL23620000 | 0.81 | ANO1 (0.48) | P2RX4ANO1KCNJ5KCNJ3RORA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |