Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 13/20 | 0.57 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716017 | 0.83 | LMNA (0.65) | LMNA | |
| Hydrochloric Acid SCHEMBL7268561 | 0.78 | KLKB1 (0.65) | F11KLKB1PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7268563 | 0.78 | KLKB1 (0.65) | F11KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL9912035 | 0.78 | LMNA (0.60) | LMNA | |
| SCHEMBL15443413 | 0.75 | RECQL (0.58) | LMNA | |
| SCHEMBL19883316 | 0.75 | RECQL (0.58) | LMNA | |
| SCHEMBL3696104 | 0.74 | MEN1 (0.66) | F11KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL5097508 | 0.74 | MEN1 (0.47) | PRSS1F10F2 | |
| SCHEMBL3696100 | 0.74 | MEN1 (0.66) | F11KLKB1PRSS1PRSS2PRSS3 | |
| SCHEMBL27858825 | 0.74 | LMNA (0.55) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136390-A1 | BLOOD COAGULATION FACTOR XIA INHIBITOR | 上海京新生物医药有限公司 | 2021-07-08 | — | — | WO | disclosed |