Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.49 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 7/20 | 0.41 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713270 | 0.91 | RECQL (0.45) | RECQLP2RX7ANO1ROCK2ALDH1A1 | |
| SCHEMBL23620098 | 0.91 | RECQL (0.43) | RECQLP2RX7GALR3NR2F2KMT2A | |
| SCHEMBL23619949 | 0.90 | ANO1 (0.47) | ANO1NR2E1ROCK2 | |
| SCHEMBL23620035 | 0.88 | RECQL (0.39) | RECQLP2RX7ANO1NR2E1ALDH1A1 | |
| SCHEMBL23620047 | 0.85 | ANO1 (0.49) | RECQLP2RX7KMT2AMEN1ANO1 | |
| SCHEMBL23619709 | 0.84 | RECQL (0.52) | RECQLP2RX7GALR3NR2F2MAPT | |
| SCHEMBL30812813 | 0.84 | RECQL (0.52) | RECQLP2RX7GALR3NR2F2MAPT | |
| SCHEMBL23620202 | 0.84 | SMN1; SMN2 (0.39) | RECQLKMT2AMAPTANO1 | |
| SCHEMBL23620196 | 0.83 | SMN1; SMN2 (0.40) | RECQLKMT2AMAPTANO1ALDH1A1 | |
| SCHEMBL23620199 | 0.81 | SMN1; SMN2 (0.45) | RECQLKMT2AMAPTANO1NR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |