SCHEMBL23620098

SCHEMBL23620098

COc1nccc2c(SN)cc(NC(=O)Cc3ccc(P)cc3Cl)cc12

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.43
P2RX7 Q99572 1/20 0.40
ANO1 Q5XXA6 6/20 0.35
CSF1R P07333 2/20 0.34
PDGFRB P09619 2/20 0.34
KDR P35968 2/20 0.34
FLT3 P36888 1/20 0.34
NR2E1 Q9Y466 2/20 0.34
RORA P35398 1/20 0.34
RORC P51449 1/20 0.34
GALR3 O60755 1/20 0.33
NR2F2 P24468 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ROCK2 O75116 1/20 0.33
ROCK1 Q13464 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23619780 0.91 RECQL (0.53) RECQLP2RX7ANO1NR2E1GALR3
SCHEMBL24713270 0.89 RECQL (0.45) RECQLP2RX7ANO1CSF1RPDGFRB
SCHEMBL23619949 0.88 ANO1 (0.47) ANO1NR2E1RORAROCK2ROCK1
SCHEMBL23620035 0.86 RECQL (0.39) RECQLP2RX7ANO1CSF1RPDGFRB
SCHEMBL23620047 0.84 ANO1 (0.49) RECQLP2RX7ANO1CSF1RPDGFRB
SCHEMBL23619627 0.81 P2RX4 (0.44) ANO1NR2E1RORARORC
SCHEMBL23620199 0.80 SMN1; SMN2 (0.45) RECQLANO1NR2E1SMN1; SMN2KMT2A
SCHEMBL23619976 0.80 ANO1 (0.49) RECQLANO1NR2E1RORCSMN1; SMN2
SCHEMBL23620024 0.80 SMN1; SMN2 (0.47) ANO1CSF1RPDGFRBKDRSMN1; SMN2
SCHEMBL23620062 0.79 ANO1 (0.48) RECQLANO1NR2E1RORAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021136238-A1 FUSED RING COMPOUND AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2021-07-08 WO disclosed