SCHEMBL23620196

SCHEMBL23620196

COc1nccc2c(SN)cc(NC(=O)Cc3c(Cl)ccc(F)c3F)cc12

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.40
MAPT P10636 2/20 0.37
ANO1 Q5XXA6 3/20 0.36
P2RX4 Q99571 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CSF1R P07333 1/20 0.35
RET P07949 1/20 0.35
PDGFRB P09619 1/20 0.35
KIT P10721 1/20 0.35
PDGFRA P16234 1/20 0.35
DDR1 Q08345 1/20 0.35
LMNA P02545 1/20 0.35
RORC P51449 1/20 0.35
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23620202 0.92 SMN1; SMN2 (0.39) SMN1; SMN2MAPTANO1P2RX4TSHR
SCHEMBL23620027 0.89 SMN1; SMN2 (0.53) SMN1; SMN2MAPTTSHRKMT2ANPSR1
SCHEMBL23620035 0.85 RECQL (0.39) SMN1; SMN2ANO1CSF1RRETPDGFRB
SCHEMBL30812914 0.85 P2RX4 (0.44) SMN1; SMN2MAPTANO1P2RX4
SCHEMBL23619872 0.85 P2RX4 (0.44) SMN1; SMN2MAPTANO1P2RX4
SCHEMBL23620047 0.85 ANO1 (0.49) SMN1; SMN2ANO1P2RX4TSHRKMT2A
SCHEMBL23619976 0.85 ANO1 (0.49) SMN1; SMN2MAPTANO1P2RX4TSHR
SCHEMBL23620199 0.85 SMN1; SMN2 (0.45) SMN1; SMN2MAPTANO1P2RX4TSHR
SCHEMBL24713270 0.83 RECQL (0.45) SMN1; SMN2ANO1P2RX4CSF1RPDGFRB
SCHEMBL23619780 0.83 RECQL (0.53) MAPTANO1KMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4079724-A1 FUSED RING COMPOUND AND APPLICATION THEREOF Wuhan LL Science and Technology Development Co., Ltd. (CN) 2022-10-26 EP disclosed
WO-2021136238-A1 FUSED RING COMPOUND AND APPLICATION THEREOF 武汉朗来科技发展有限公司 2021-07-08 WO disclosed