Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 11/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10025483 | 0.84 | NOS1 (0.42) | TLR8 | |
| SCHEMBL23479163 | 0.84 | NPC1 (0.50) | TLR8POLB | |
| Hydrochloric Acid SCHEMBL21437120 | 0.75 | TRPV1 (0.52) | — | |
| SCHEMBL18965901 | 0.73 | KDM4E (0.43) | TLR8POLB | |
| SCHEMBL1704421 | 0.72 | TLR8 (0.58) | TLR8TLR7 | |
| SCHEMBL21653630 | 0.72 | SKP2 (0.46) | SKP2HSD11B1 | |
| SCHEMBL979518 | 0.72 | TLR8 (0.58) | TLR8TLR7 | |
| SCHEMBL15356364 | 0.72 | TLR8 (0.40) | TLR8PSMB5HSD11B1 | |
| SCHEMBL23490723 | 0.71 | NPC1 (0.46) | TLR8POLB | |
| SCHEMBL9762807 | 0.71 | RAB9A (0.71) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011099832-A2 | NOVEL BENZIMIDAZOLE COMPOUND, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CRYSTALGENOMICS, INC. (KR) | 2011-08-18 | — | — | WO | disclosed |