Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.31 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619729 | 0.86 | LMNA (0.35) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL20160783 | 0.79 | NR4A2 (0.37) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL25256354 | 0.78 | LMNA (0.39) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL24713528 | 0.77 | LMNA (0.38) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL23619987 | 0.74 | — | — | |
| SCHEMBL23619928 | 0.72 | HIPK2 (0.36) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL23619727 | 0.70 | LMNA (0.37) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL23619761 | 0.69 | HIPK2 (0.36) | LMNACYP3A4MAPTAPEX1MAPK1 | |
| SCHEMBL30517096 | 0.69 | ALDH1A1 (0.43) | LMNAMAPTMAPK1HTT | |
| SCHEMBL12266517 | 0.67 | LMNA (0.60) | LMNACYP3A4MAPTAPEX1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |