Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620199 | 0.91 | SMN1; SMN2 (0.45) | ANO1SMN1; SMN2MAPTRECQLTHRB | |
| SCHEMBL23620027 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTTSHRKMT2ANPSR1 | |
| SCHEMBL23619949 | 0.86 | ANO1 (0.47) | ANO1P2RX4NR2E1 | |
| SCHEMBL23620202 | 0.86 | SMN1; SMN2 (0.39) | ANO1SMN1; SMN2MAPTRECQLP2RX4 | |
| SCHEMBL30812901 | 0.85 | ANO1 (0.52) | ANO1SMN1; SMN2P2RX4LMNA | |
| SCHEMBL23619951 | 0.85 | ANO1 (0.52) | ANO1SMN1; SMN2P2RX4LMNA | |
| SCHEMBL23620196 | 0.85 | SMN1; SMN2 (0.40) | ANO1SMN1; SMN2MAPTRECQLP2RX4 | |
| SCHEMBL23619780 | 0.81 | RECQL (0.53) | ANO1MAPTRECQLTHRBKMT2A | |
| SCHEMBL23620035 | 0.81 | RECQL (0.39) | ANO1SMN1; SMN2RECQLNR2E1RORC | |
| SCHEMBL23620213 | 0.81 | ANO1 (0.40) | ANO1SMN1; SMN2MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |