Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619949 | 0.86 | ANO1 (0.47) | NR2E1MAPK8MAPK9 | |
| SCHEMBL23619952 | 0.85 | P2RX4 (0.42) | NR2E1MEN1TSHRKMT2AMAPK8 | |
| SCHEMBL30812907 | 0.85 | P2RX4 (0.42) | NR2E1MEN1TSHRKMT2AMAPK8 | |
| SCHEMBL23620213 | 0.83 | ANO1 (0.40) | MEN1TSHRKMT2AMAPK8MAPK9 | |
| SCHEMBL23620207 | 0.82 | MEN1 (0.44) | MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL24713235 | 0.80 | ANO1 (0.38) | MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL23619780 | 0.80 | RECQL (0.53) | NR2E1MEN1KMT2AP2RX7 | |
| SCHEMBL23620024 | 0.80 | SMN1; SMN2 (0.47) | MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL23620035 | 0.79 | RECQL (0.39) | NR2E1P2RX7SMN1; SMN2 | |
| SCHEMBL23620098 | 0.78 | RECQL (0.43) | NR2E1MEN1TSHRKMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |