Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 10/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23620142 | 0.94 | LRRK2 (0.38) | LRRK2IRAK4HCRTR1HCRTR2 | |
| SCHEMBL23620095 | 0.84 | LRRK2 (0.49) | LRRK2IRAK4ACACBLOXLOXL2 | |
| SCHEMBL25144094 | 0.81 | LRRK2 (0.43) | LRRK2IRAK4ACACBLOXLOXL2 | |
| SCHEMBL25144091 | 0.78 | LRRK2 (0.46) | LRRK2ACACBLOXLOXL2JAK3 | |
| SCHEMBL24713380 | 0.78 | LRRK2 (0.41) | LRRK2 | |
| SCHEMBL24224724 | 0.76 | LRRK2 (0.43) | LRRK2ALOX5APFEN1JAK3CYP19A1 | |
| SCHEMBL26505588 | 0.75 | LRRK2 (0.45) | LRRK2ALOX5APFEN1JAK3CYP19A1 | |
| SCHEMBL23620231 | 0.74 | CCNB2 (0.36) | LRRK2 | |
| SCHEMBL24713250 | 0.74 | LRRK2 (0.36) | LRRK2ACACBALOX5APFEN1 | |
| SCHEMBL24713323 | 0.73 | LRRK2 (0.35) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |