Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 13/20 | 0.49 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24713380 | 0.94 | LRRK2 (0.41) | LRRK2GPR119 | |
| SCHEMBL23620145 | 0.84 | LRRK2 (0.46) | LRRK2ACACBLOXLOXL2ALOX5AP | |
| SCHEMBL25144091 | 0.78 | LRRK2 (0.46) | LRRK2ACACBLOXLOXL2 | |
| SCHEMBL23620142 | 0.78 | LRRK2 (0.38) | LRRK2IRAK4 | |
| SCHEMBL19443692 | 0.76 | LRRK2 (0.55) | LRRK2LOXLOXL2 | |
| SCHEMBL14853043 | 0.74 | CCR1 (0.39) | LRRK2 | |
| SCHEMBL24713250 | 0.74 | LRRK2 (0.36) | LRRK2ACACBALOX5APFEN1 | |
| SCHEMBL24713323 | 0.73 | LRRK2 (0.35) | LRRK2 | |
| SCHEMBL27340986 | 0.72 | OPRL1 (0.33) | — | |
| SCHEMBL25144094 | 0.72 | LRRK2 (0.43) | LRRK2ACACBLOXLOXL2ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4079724-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | Wuhan LL Science and Technology Development Co., Ltd. (CN) | 2022-10-26 | — | — | EP | disclosed |
| WO-2021136238-A1 | FUSED RING COMPOUND AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2021-07-08 | — | — | WO | disclosed |