SCHEMBL23620372

SCHEMBL23620372

OC1(c2cccc(Cl)c2)C2CC3CC(C2)CC1C3

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 8/20 0.58
SLC6A3 Q01959 7/20 0.41
SLC6A4 P31645 6/20 0.41
CHRNA1 P02708 5/20 0.41
CHRNB1 P11230 5/20 0.41
CHRNB2 P17787 5/20 0.41
SLC6A2 P23975 5/20 0.41
CHRNB4 P30926 5/20 0.41
CHRNA3 P32297 5/20 0.41
CHRNA4 P43681 5/20 0.41
CHRNG P07510 4/20 0.41
CHRND Q07001 4/20 0.41
HTR2C P28335 2/20 0.39
HTR2A P28223 1/20 0.39
HTR2B P41595 1/20 0.39
P2RX7 Q99572 1/20 0.38
NR1H4 Q96RI1 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23620590 0.82 HSD11B1 (0.57) HSD11B1SLC6A3SLC6A4CHRNA1CHRNB1
SCHEMBL6898977 0.79 CHRNA1 (0.43) HSD11B1SLC6A3CHRNA1CHRNB1CHRNB2
SCHEMBL18905253 0.79 HSD11B1 (0.38) HSD11B1
SCHEMBL6891957 0.78 HSD11B1 (0.54) HSD11B1SLC6A3SLC6A4CHRNA1CHRNB1
SCHEMBL6896759 0.77 HSD11B1 (0.53) HSD11B1
SCHEMBL7079057 0.76 KDM1A (0.50) SLC6A3SLC6A4SLC6A2SMN1; SMN2
SCHEMBL21002189 0.76 KDM1A (0.49) HSD11B1SLC6A3SLC6A4CHRNA1CHRNB1
SCHEMBL30791157 0.76 KDM1A (0.49) HSD11B1SLC6A3SLC6A4CHRNA1CHRNB1
SCHEMBL6899454 0.76 HSD11B1 (0.39) HSD11B1SMN1; SMN2
SCHEMBL13216344 0.74 HSD11B1 (1.00) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135750-A1 ORGANIC COMPOUND, APPLICATION THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed