Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23666532 | 0.89 | AKR1C4 (0.42) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL25113117 | 0.89 | AKR1C4 (0.42) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL25567374 | 0.86 | PTGS1 (0.38) | — | |
| SCHEMBL22540222 | 0.85 | AKR1C4 (0.38) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL22073992 | 0.82 | KDM4E (0.41) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL10066623 | 0.81 | L3MBTL1 (0.40) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL23615490 | 0.80 | AKR1C4 (0.37) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL19784507 | 0.80 | KDM4E (0.33) | KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL21011023 | 0.78 | L3MBTL1 (0.59) | KDM4EATML3MBTL1HDAC4PTPN1 | |
| SCHEMBL25159601 | 0.78 | L3MBTL1 (0.59) | KDM4EATML3MBTL1HDAC4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136064-A1 | NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE, AND ELECTRONIC APPARATUS | 陕西莱特光电材料股份有限公司 | 2021-07-08 | — | — | WO | disclosed |