SCHEMBL23620907

SCHEMBL23620907

CC(C)(C)OC(=O)N(CCN(C(=O)OC(C)(C)C)c1ccc(N)cn1)c1ccc(N)cn1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 1/20 0.34
HDAC1 Q13547 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
F2 P00734 3/20 0.33
CKS1B P61024 1/20 0.33
SKP1 P63208 1/20 0.33
SKP2 Q13309 1/20 0.33
HCAR3 P49019 2/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
AAK1 Q2M2I8 2/20 0.32
CSNK2A1 P68400 2/20 0.32
CSNK2A2 P19784 1/20 0.32
SYK P43405 1/20 0.32
AOC3 Q16853 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29392374 1.00 SSTR4 (0.34) SSTR4HDAC1HDAC8HDAC6F2
SCHEMBL26640862 0.95 PHLPP2 (0.36) SSTR4HDAC1HDAC8HDAC6F2
SCHEMBL30648808 0.95 PHLPP2 (0.36) SSTR4HDAC1HDAC8HDAC6F2
SCHEMBL18519393 0.91 CSNK2A1 (0.35) SSTR4F2KDM4ERAB9ACSNK2A1
SCHEMBL19674226 0.90 AOC3 (0.34) SSTR4HDAC1HDAC8HDAC6HCAR3
SCHEMBL29392135 0.87 CKS1B (0.36) HDAC1HDAC8HDAC6CKS1BSKP1
SCHEMBL6018932 0.84 SYK (0.37) SSTR4KDM4EPOLBRAB9ASYK
SCHEMBL6645347 0.83 LMNA (0.36) KDM4ERAB9ACSNK2A1CSNK2A2
SCHEMBL8723112 0.82 KDM4E (0.34) SSTR4KDM4EPOLBRAB9ASYK
SCHEMBL56808 0.82 TTK (0.37) SSTR4CKS1BSKP1SKP2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11061282-B2 Liquid crystal aligning agent, liquid crystal alignment film, method for producing same, liquid crystal element and polymer JSR CORPORATION (JP) 2021-07-13 US disclosed
US-11061282-B2 Liquid crystal aligning agent, liquid crystal alignment film, method for producing same, liquid crystal element and polymer JSR CORPORATION (JP) 2021-07-13 US disclosed