Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6018932 | 0.86 | SYK (0.37) | KDM4EPOLBRAB9AALDH1A1NR1H2 | |
| SCHEMBL56808 | 0.85 | TTK (0.37) | KDM4EPOLBRAB9AALDH1A1NR1H2 | |
| SCHEMBL2558802 | 0.82 | HCAR3 (0.48) | ALDH1A1 | |
| SCHEMBL23620907 | 0.82 | SSTR4 (0.34) | KDM4EPOLBRAB9ASSTR4SYK | |
| SCHEMBL29392374 | 0.82 | SSTR4 (0.34) | KDM4EPOLBRAB9ASSTR4SYK | |
| SCHEMBL30676213 | 0.81 | USP30 (0.43) | KDM4EPOLBRAB9AALDH1A1NR1H2 | |
| SCHEMBL19674226 | 0.81 | AOC3 (0.34) | KDM4EPOLBRAB9AGPR119SSTR4 | |
| SCHEMBL26826927 | 0.81 | USP30 (0.43) | KDM4EPOLBRAB9AALDH1A1NR1H2 | |
| SCHEMBL28781892 | 0.80 | MEN1 (0.34) | POLBALDH1A1USP30 | |
| SCHEMBL7913868 | 0.79 | CYP2C19 (0.49) | KDM4EPOLBRAB9AALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753520-A | BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING | JOHNSON MATTHEY INC. (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0384769-B1 | Protein labelling | JOHNSON MATTHEY PLC (GB) | 1996-04-24 | — | — | EP | disclosed |
| US-5420285-A | Imaging for medicine | JOHNSON MATTHEY, INC. (US) | 1995-05-30 | — | — | US | disclosed |
| EP-0384769-A2 | Protein labelling | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1990-08-29 | — | — | EP | disclosed |