SCHEMBL2362149

SCHEMBL2362149

CCCC[CH][Si](C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2361315 0.93 TSHR (0.37) TSHRALDH1A1
SCHEMBL2361683 0.84 TSHR (0.30) TSHRALDH1A1
SCHEMBL2361867 0.78 TSHR (0.35) TSHRALDH1A1
SCHEMBL2361174 0.77 TSHR (0.38) TSHRALDH1A1
SCHEMBL3082951 0.76 TSHR (0.33) TSHRALDH1A1
SCHEMBL3082948 0.76 TSHR (0.33) TSHRALDH1A1
SCHEMBL815537 0.73
SCHEMBL2361838 0.71 TSHR (0.36) TSHRALDH1A1
SCHEMBL8330744 0.71 TSHR (0.41) TSHR
SCHEMBL2360955 0.70 TSHR (0.39) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2231740-B1 MOISTURE-CURABLE SILYLATED POLYUREA AND ADHESIVE, SEALANT AND COATING COMPOSITIONS CONTAINING SAME MOMENTIVE PERFORMANCE MAT INC (US) 2011-08-24 EP claimed