SCHEMBL3082948

SCHEMBL3082948

CCCC/C=C/[Si](C)(OC)OC

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
ALDH1A1 P00352 3/20 0.33
LPAR2 Q9HBW0 2/20 0.32
LPAR3 Q9UBY5 2/20 0.32
LPAR1 Q92633 1/20 0.32
F7 P08709 1/20 0.32
F3 P13726 1/20 0.32
FAAH O00519 3/20 0.32
TRPV1 Q8NER1 1/20 0.32
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
PLA2G4A P47712 1/20 0.30
PAFAH1B2 P68402 1/20 0.30
KMT2A Q03164 1/20 0.30
MGLL Q99685 1/20 0.30
ABHD6 Q9BV23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3082951 1.00 TSHR (0.33) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL4354197 0.93 FAAH (0.40) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL4354195 0.93 FAAH (0.40) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL4366313 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL4348922 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL4349949 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL4365366 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL4366312 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL4365363 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1
SCHEMBL4348917 0.91 FAAH (0.43) F7F3FAAHTRPV1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140102332-A1 FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2014-04-17 US claimed
EP-1769512-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS Dow Corning Corporation (US) 2007-04-04 EP claimed
WO-2005124792-A1 ANTI-CORROSION ADDITIVE FOR ELECTRICAL CABLE RESTORATION FLUIDS DOW CORNING CORPORATION (US) 2005-12-29 WO claimed
EP-3645607-B1 METHOD FOR HYDROSILYLATION OF ALIPHATICALLY UNSATURATED ALKOXYSILANES AND HYDROGEN TERMINATED ORGANOSILOXANE OLIGOMERS TO PREPARE ALKOXYSILYL TERMINATED POLYMERS USEFUL FOR FUNCTIONALIZING POLYORGANOSILOXANES USING AN IRIDIUM CATALYST DOW SILICONES CORP (US) 2025-11-05 EP disclosed
EP-4617310-A1 RUBBER COMPOSITION AND ORGANOPOLYSILOXANE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-17 EP disclosed
US-20250282914-A1 ORGANOPOLYSILOXANE CONTAINING MERCAPTO GROUP AND ALKOXYSILYL GROUP, AND COMPOSITION COMPRISING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-11 US disclosed
EP-4520778-A1 ORGANOPOLYSILOXANE CONTAINING MERCAPTO GROUP AND ALKOXYSILYL GROUP, AND COMPOSITION COMPRISING SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-03-12 EP disclosed
EP-3645606-B1 METHOD FOR HYDROSILYLATION OF ALIPHATICALLY UNSATURATED ALKOXYSILANES AND HYDROGEN TERMINATED ORGANOSILOXANE OLIGOMERS TO PREPARE ALKOXYSILYL TERMINATED POLYMERS USEFUL FOR FUNCTIONALIZING POLYORGANOSILOXANES USING A RHODIUM CATALYST DOW SILICONES CORP (US) 2024-06-26 EP disclosed
EP-3645608-B1 METHOD FOR HYDROSILYLATION OF ALIPHATICALLY UNSATURATED ALKOXYS I LAN ES AND HYDROGEN TERMINATED ORGANOSILOXANE OLIGOMERS TO PREPARE ALKOXYSILYL TERMINATED POLYMERS USEFUL FOR FUNCTIONALIZING POLYORGANOSILOXANES USING A COBALT CATALYST DOW SILICONES CORP (US) 2024-06-19 EP disclosed
WO-2024101082-A1 RUBBER COMPOSITION AND ORGANOPOLYSILOXANE 信越化学工業株式会社 2024-05-16 WO disclosed
WO-2023214526-A1 ORGANOPOLYSILOXANE CONTAINING MERCAPTO GROUP AND ALKOXYSILYL GROUP, AND COMPOSITION COMPRISING SAME 信越化学工業株式会社 2023-11-09 WO disclosed
EP-0755963-A2 Method for producing alkoxysilalkylene terminated siloxane polymers DOW CORNING CORPORATION (US) 1997-01-29 EP disclosed
EP-0586240-B1 Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom DOW CORNING (US) 1996-12-18 EP disclosed
US-5545704-A ENDCAPPING WITH A SILAZANE INPRESENCE OF ACID CATALYST; THEN REACTING WITH AN ALKOXYSILANE IN PRESENCE OF A HYDROSILYLATION CATALYST DOW CORNING CORPORATION (US) 1996-08-13 US disclosed
EP-0586240-A2 Alkoxy endblocked polydiorganosiloxane and room temperature vulcanizable silicone elastomers made therefrom DOW CORNING CORPORATION (US) 1994-03-09 EP disclosed
EP-0586241-A1 Azasilacycloalkyl functional alkoxysilanes and azasilacycloalkyl functional tetramethyldisiloxanes DOW CORNING CORPORATION (US) 1994-03-09 EP disclosed
US-5276123-A Endblocking polysiloxanes DOW CORNING CORPORATION (US) 1994-01-04 US disclosed
US-5239099-A Room temperature vulcanization; noncorrosive byproducts DOW CORNING CORPORATION (US) 1993-08-24 US disclosed
EP-0421644-A2 Method for preparation of organoalkoxysilanes DOW CORNING CORPORATION (US) 1991-04-10 EP disclosed
US-4924022-A Method for preparation of organoalkoxysilanes DOW CORNING CORPORATION (US) 1990-05-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140102332-A1 FUNCTIONAL REINFORCING FILLERS MODIFIED WITH ALKENYLALKOXYSILANE AND PREPARING METHOD OF THE SAME TST, MSN, TELO2 TSHR 656/4885ALDH1A1 993/4885LPAR2 3176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.