SCHEMBL23622110

SCHEMBL23622110

Cc1cn([C@H]2CC[C@@](F)(CO)O2)c(=O)[nH]c1=S

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TK1 P04183 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23622010 0.88 TK1 (0.49) TK1
SCHEMBL21345570 0.87 LMNA (0.40) TK1
SCHEMBL21345791 0.86 TK1 (0.41) TK1
SCHEMBL21346002 0.86 TK1 (0.34) TK1
SCHEMBL23622093 0.86 TK1 (0.34) TK1
SCHEMBL23622008 0.84 TK1 (0.33) TK1
SCHEMBL21345820 0.84 TK1 (0.44) TK1
SCHEMBL21345258 0.81 POLB (0.42) TK1
SCHEMBL21345563 0.80 LMNA (0.52)
SCHEMBL21345270 0.80 POLB (0.45) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021137913-A2 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO EMORY UNIVERSITY (US) 2021-07-08 WO disclosed