SCHEMBL23622149

SCHEMBL23622149

c1ccc([Si](c2ccccc2)(c2ccc(-c3cc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)n3)cc2)c2ccc(-c3nc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)n3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.38
NPSR1 Q6W5P4 4/20 0.38
MAPK1 P28482 4/20 0.38
HSD17B10 Q99714 2/20 0.38
TSHR P16473 1/20 0.38
HPGD P15428 5/20 0.36
MEN1 O00255 6/20 0.35
KMT2A Q03164 6/20 0.35
ALDH1A1 P00352 4/20 0.35
NTSR1 P30989 1/20 0.35
ADORA1 P30542 2/20 0.33
ADORA2A P29274 1/20 0.33
ATM Q13315 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
KDM4E B2RXH2 3/20 0.32
LMNA P02545 1/20 0.32
GLA P06280 1/20 0.32
ADORA3 P0DMS8 1/20 0.31
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874906 0.96 MAPK1 (0.40) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL23622588 0.95 L3MBTL1 (0.34) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL25874907 0.95 L3MBTL1 (0.34) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL25904519 0.93 MAPT (0.36) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL23622201 0.92 MAPT (0.37) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL23622755 0.92 MAPT (0.37) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL25949238 0.91 MAPT (0.45) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL23622650 0.90 DHODH (0.32) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL23622482 0.90 KDM4E (0.41) MAPTNPSR1MAPK1HSD17B10TSHR
SCHEMBL25949227 0.90 MAPT (0.47) MAPTNPSR1MAPK1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363254-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230363254-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-20210210700-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-07-08 US disclosed