SCHEMBL23622650

SCHEMBL23622650

c1ccc([Si](c2ccccc2)(c2ccc(-c3cc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)c3)cc2)c2ccc(-c3cc(-n4c5ccccc5c5ccccc54)nc(-n4c5ccccc5c5ccccc54)n3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.32
ATM Q13315 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 2/20 0.30
NPSR1 Q6W5P4 2/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30
GAA P10253 1/20 0.30
TUBB4A P04350 1/20 0.30
TUBB P07437 1/20 0.30
TUBA3C P0DPH7 1/20 0.30
TUBA1B P68363 1/20 0.30
TUBA4A P68366 1/20 0.30
TUBB4B P68371 1/20 0.30
TUBB3 Q13509 1/20 0.30
TUBB2A Q13885 1/20 0.30
TUBB8 Q3ZCM7 1/20 0.30
TUBA3E Q6PEY2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874907 0.95 L3MBTL1 (0.34) DHODHATML3MBTL1KDM4EMAPT
SCHEMBL23622588 0.95 L3MBTL1 (0.34) DHODHATML3MBTL1KDM4EMAPT
SCHEMBL23622482 0.90 KDM4E (0.41) DHODHATML3MBTL1KDM4EMAPT
SCHEMBL23622149 0.90 MAPT (0.38) ATML3MBTL1KDM4EMAPTNPSR1
SCHEMBL26029039 0.89 DHODH (0.31) DHODHATML3MBTL1KDM4E
SCHEMBL26880695 0.89 KDM4E (0.30) ATML3MBTL1KDM4E
SCHEMBL25874906 0.89 MAPK1 (0.40) ATML3MBTL1KDM4EMAPTNPSR1
SCHEMBL23622704 0.88 KDM4E (0.39) ATML3MBTL1KDM4ETSHRTUBB4A
SCHEMBL23622653 0.88 KDM4E (0.39) ATML3MBTL1KDM4ETSHRTUBB4A
SCHEMBL23622194 0.88 PIK3CA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230363254-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-20230363254-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-09 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-11716899-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-01 US disclosed
US-20210210700-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-07-08 US disclosed