Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 7/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623076 | 1.00 | MAP4K4 (0.44) | MAP4K4FFAR2ACACBLRRK2MAOB | |
| SCHEMBL16466967 | 0.84 | OPRK1 (0.44) | MAP4K4FFAR2ACACBOPRK1 | |
| SCHEMBL4676620 | 0.83 | MAP4K4 (0.42) | MAP4K4FFAR2ACACBLRRK2OPRK1 | |
| SCHEMBL23623183 | 0.78 | ACACB (0.41) | ACACBOPRK1 | |
| SCHEMBL23622934 | 0.78 | ACACB (0.41) | ACACBOPRK1 | |
| SCHEMBL25841222 | 0.77 | ALDH1A1 (0.44) | OPRK1 | |
| SCHEMBL23580075 | 0.77 | ALDH1A1 (0.49) | OPRK1 | |
| SCHEMBL26499774 | 0.76 | PDE10A (0.36) | FFAR2ACACBLRRK2OPRK1 | |
| SCHEMBL26499783 | 0.76 | PDE10A (0.36) | FFAR2ACACBLRRK2OPRK1 | |
| SCHEMBL23625755 | 0.76 | ALDH1A1 (0.51) | OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021138434-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-07-08 | — | — | WO | disclosed |