Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 4/20 | 0.35 |
| ▸ | FEN1 | P39748 | 4/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DNASE1 | P24855 | 2/20 | 0.33 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623421 | 0.92 | MYC (0.38) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL23611743 | 0.89 | ERCC1 (0.37) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL29930728 | 0.89 | ERCC1 (0.37) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL23623315 | 0.87 | ERCC1 (0.38) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL23623314 | 0.87 | ERCC1 (0.39) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL23623261 | 0.76 | HPGD (0.41) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL23623266 | 0.72 | HPGD (0.40) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL23611763 | 0.71 | HPGD (0.41) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL29930610 | 0.71 | HPGD (0.41) | ERCC1FEN1ERCC4HPGDALDH1A1 | |
| SCHEMBL23623298 | 0.71 | HPGD (0.40) | ERCC1FEN1ERCC4HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021138540-A1 | POLYCYCLIC AMIDES AS UBE2K MODULATORS FOR TREATING CANCER | BERG LLC (US) | 2021-07-08 | — | — | WO | disclosed |