Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23623477 | 0.77 | HSD17B10 (0.68) | HSD17B10ALDH1A1KDM4ECCNB2CDK1 | |
| SCHEMBL13929106 | 0.72 | HSD17B10 (0.69) | HSD17B10ALDH1A1KDM4ECCNB2CDK1 | |
| SCHEMBL9071981 | 0.72 | HSD17B10 (0.69) | HSD17B10ALDH1A1KDM4ECCNB2CDK1 | |
| SCHEMBL1528407 | 0.72 | HSD17B10 (0.69) | HSD17B10ALDH1A1KDM4ECCNB2CDK1 | |
| SCHEMBL28956870 | 0.72 | HSD17B10 (0.63) | HSD17B10ALDH1A1KDM4ECCNB2CDK1 | |
| SCHEMBL29930877 | 0.71 | HSD17B10 (1.00) | HSD17B10ALDH1A1KDM4ECCNB2CDK1 | |
| SCHEMBL23611724 | 0.71 | HSD17B10 (1.00) | HSD17B10ALDH1A1KDM4ECCNB2CDK1 | |
| SCHEMBL17280016 | 0.70 | HSD17B10 (0.65) | HSD17B10ALDH1A1KDM4EALOX15MEN1 | |
| SCHEMBL71938 | 0.70 | HSD17B10 (0.60) | HSD17B10ALDH1A1KDM4EALOX15CHRNA3 | |
| SCHEMBL29930951 | 0.70 | HSD17B10 (0.60) | HSD17B10ALDH1A1KDM4EALOX15CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021138540-A1 | POLYCYCLIC AMIDES AS UBE2K MODULATORS FOR TREATING CANCER | BERG LLC (US) | 2021-07-08 | — | — | WO | disclosed |