Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.36 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711301 | 1.00 | EPHX2 (0.37) | EPHX2EPHX1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL23624042 | 1.00 | EPHX2 (0.37) | EPHX2EPHX1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL2018433 | 0.84 | SPR (0.34) | SPRALDH1A1NPC1 | |
| SCHEMBL23624210 | 0.84 | EPHX2 (0.37) | EPHX2EPHX1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL6631486 | 0.81 | EPHX2 (0.40) | EPHX2EPHX1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL21075577 | 0.81 | CHRNB2 (0.45) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL21075766 | 0.81 | CHRNB2 (0.45) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL17643421 | 0.81 | EPHX2 (0.40) | EPHX2EPHX1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL22991068 | 0.80 | EPHX2 (0.37) | EPHX2EPHX1CHRNB2CHRNA3CHRNA4 | |
| SCHEMBL22991066 | 0.80 | EPHX2 (0.37) | EPHX2EPHX1CHRNB2CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136354-A1 | BIPHENYL DERIVATIVE INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2021-07-08 | — | — | WO | disclosed |