SCHEMBL23624364

SCHEMBL23624364

N#Cc1cccc(-c2ccc3c4c(ccc(Cl)c24)-c2ccccc2-3)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2C P18825 1/20 0.51
PTGDR2 Q9Y5Y4 1/20 0.42
PDK2 Q15119 1/20 0.42
KCNA5 P22460 1/20 0.42
KCNH2 Q12809 1/20 0.42
CLK4 Q9HAZ1 1/20 0.41
MAOB P27338 1/20 0.41
CHEK1 O14757 1/20 0.41
ENPP1 P22413 1/20 0.40
EIF4E P06730 1/20 0.40
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA1 P14867 1/20 0.38
CREBBP Q92793 1/20 0.38
LRRK2 Q5S007 3/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
PGR P06401 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23624370 0.87 PDK2 (0.41) ADRA2CPDK2MAOBCHEK1GABRG2
SCHEMBL23624444 0.84 CYP11B1 (0.43) ADRA2CPDK2EIF4E
SCHEMBL23624678 0.83 CYP11B1 (0.39) ADRA2CPDK2EIF4EADORA2AADORA1
SCHEMBL23624366 0.83 PDK2 (0.38) PDK2MAOBEIF4EADORA2AADORA1
SCHEMBL23624368 0.81 PDK2 (0.40) PDK2MAOBEIF4EGABRG2GABRB3
SCHEMBL28022368 0.80 ADRA2C (0.59) ADRA2CPTGDR2PDK2KCNA5KCNH2
SCHEMBL23624644 0.80 PDK2 (0.38) PDK2MAOBEIF4EADORA2AADORA1
SCHEMBL26272700 0.80 ADRA2C (0.48) ADRA2CPTGDR2PDK2KCNA5KCNH2
SCHEMBL23624369 0.78 CYP1A2 (0.51) ADRA2CCLK4GABRG2GABRB3GABRA5
SCHEMBL13170901 0.78 ADRA2C (0.50) ADRA2CPDK2CLK4MAOBCHEK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135725-A1 ORGANIC COMPOUND, ELECTRONIC DEVICE AND ELECTRONIC APPARATUS USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed