⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20090726 | 0.69 | NCF1 (0.34) | — | |
| SCHEMBL19135303 | 0.67 | — | — | |
| SCHEMBL23624918 | 0.62 | — | — | |
| SCHEMBL23108525 | 0.61 | — | — | |
| SCHEMBL20090528 | 0.61 | — | — | |
| SCHEMBL209495 | 0.60 | — | — | |
| SCHEMBL23625108 | 0.60 | NCF1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL28503994 | 0.58 | RAB9A (0.38) | — | |
| Sulfuric Acid SCHEMBL28501743 | 0.56 | RAB9A (0.38) | — | |
| SCHEMBL12854185 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021138391-A1 | INDAZOLE COMPOUNDS | TYRA BIOSCIENCES, INC. (US) | 2021-07-08 | — | — | WO | disclosed |
| WO-2021138392-A1 | AMINOPYRIMIDINE COMPOUNDS | TYRA BIOSCIENCES, INC. (US) | 2021-07-08 | — | — | WO | disclosed |