Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.60 |
| ▸ | CA1 | P00915 | 5/20 | 0.60 |
| ▸ | CA2 | P00918 | 5/20 | 0.60 |
| ▸ | CA9 | Q16790 | 5/20 | 0.60 |
| ▸ | PTPRF | P10586 | 2/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625179 | 0.88 | CA12 (0.62) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL18326514 | 0.83 | CA12 (0.71) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL23625183 | 0.83 | CA12 (0.71) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL23625146 | 0.81 | CA12 (0.67) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL19940249 | 0.80 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL18329586 | 0.80 | CA12 (0.74) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL29459238 | 0.79 | CA12 (0.69) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL23625184 | 0.79 | CA12 (0.62) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL12058748 | 0.78 | CA12 (0.72) | CA12CA1CA2CA9PTPRF | |
| SCHEMBL21524959 | 0.78 | CA12 (0.78) | CA12CA1CA2CA9PTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206791-A1 | SELECTIVE METAL-MEDIATED ARYLATION OF DICHALCOGENIDES IN BIOMOLECULES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206791-A1 | SELECTIVE METAL-MEDIATED ARYLATION OF DICHALCOGENIDES IN BIOMOLECULES | SCLY, SELENOI, PTMS | CA12 195/4885CA1 430/4885CA2 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.