Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.30 |
| ▸ | HTR2C | P28335 | 3/20 | 0.30 |
| ▸ | HTR2B | P41595 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22122671 | 0.84 | HRH4 (0.32) | HRH4 | |
| SCHEMBL20614145 | 0.81 | SLC6A4 (0.30) | SLC6A4NR1I2KCNH2GRM2 | |
| SCHEMBL20614149 | 0.78 | NR1I2 (0.32) | SLC6A4NR1I2KCNH2GRM2 | |
| SCHEMBL22145558 | 0.78 | IL1B (0.36) | BRD4HTR2AHTR2CHTR2BKCNH2 | |
| SCHEMBL21095479 | 0.77 | NR1I2 (0.31) | NR1I2KCNH2GRM2 | |
| SCHEMBL22145777 | 0.77 | PIM1 (0.34) | HRH4BRD4HTR2AHTR2CHTR2B | |
| SCHEMBL20614177 | 0.76 | — | — | |
| SCHEMBL23625265 | 0.75 | — | — | |
| SCHEMBL22145709 | 0.74 | — | — | |
| SCHEMBL170373 | 0.73 | SLC6A4 (0.34) | BRD4SLC6A4NR1I2KCNH2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017812-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023180505-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2023-09-28 | — | — | WO | disclosed |
| US-11447701-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2022-09-20 | — | — | US | disclosed |
| EP-4015598-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2022-06-22 | — | — | EP | disclosed |
| US-20210207029-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447701-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | NEFM, FES, SBDS | HRH4 4246/4885BRD4 3464/4885CYP2D6 3456/4885 |
| US-20210207029-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | NEFM, FES, SBDS | HRH4 4246/4885BRD4 3464/4885CYP2D6 3456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.