Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23900563 | 1.00 | BTK (0.44) | BTKDGAT1GAAHSD11B1KDM1A | |
| SCHEMBL24543130 | 1.00 | BTK (0.44) | BTKDGAT1GAAHSD11B1KDM1A | |
| SCHEMBL23562416 | 0.86 | HSD11B1 (0.49) | BTKGAAHSD11B1KDM1ANFKB1 | |
| SCHEMBL26014913 | 0.86 | HSD11B1 (0.48) | BTKGAAHSD11B1KDM1ANFKB1 | |
| SCHEMBL24337073 | 0.86 | HSD11B1 (0.49) | BTKGAAHSD11B1KDM1ANFKB1 | |
| SCHEMBL26014916 | 0.83 | HSD11B1 (0.39) | BTKGAAHSD11B1KDM1AMAOB | |
| SCHEMBL1847058 | 0.79 | HSD11B1 (0.56) | BTKDGAT1HSD11B1KMT2AHSD11B2 | |
| SCHEMBL1847057 | 0.79 | HSD11B1 (0.56) | BTKDGAT1HSD11B1KMT2AHSD11B2 | |
| SCHEMBL974112 | 0.79 | HSD11B1 (0.56) | BTKDGAT1HSD11B1KMT2AHSD11B2 | |
| SCHEMBL974114 | 0.79 | HSD11B1 (0.56) | BTKDGAT1HSD11B1KMT2AHSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136461-A1 | PURINE DERIVATIVE AND MEDICAL USE THEREOF | 成都百裕制药股份有限公司 | 2021-07-08 | — | — | WO | disclosed |