SCHEMBL23625535

SCHEMBL23625535

N#Cc1ccc(-c2ccc(I)cc2)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.45
IMPDH2 P12268 2/20 0.44
IMPDH1 P20839 2/20 0.44
ESR2 Q92731 1/20 0.42
CYP11B1 P15538 1/20 0.37
CYP11B2 P19099 1/20 0.37
SLC22A12 Q96S37 9/20 0.37
DYRK1A Q13627 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 2/20 0.35
GAA P10253 2/20 0.35
MAPT P10636 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
GALR3 O60755 1/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2350899 0.84 IMPDH2 (0.50) ARIMPDH2IMPDH1ESR2SLC22A12
SCHEMBL6152302 0.81 IMPDH2 (0.49) ARIMPDH2IMPDH1ESR2SLC22A12
SCHEMBL25546169 0.81 AR (0.45) ARIMPDH2IMPDH1ESR2CYP11B1
SCHEMBL24407116 0.81 AR (0.45) ARIMPDH2IMPDH1ESR2CYP11B1
SCHEMBL23624462 0.80 IMPDH2 (0.47) ARIMPDH2IMPDH1ESR2SLC22A12
SCHEMBL16917824 0.80 IMPDH2 (0.57) ARIMPDH2IMPDH1SLC22A12KDM4E
SCHEMBL4373221 0.79 ESR2 (0.66) ARESR2ALDH1A1CYP1A2HPGD
SCHEMBL24406867 0.77 CA1 (0.46) ARIMPDH2IMPDH1ESR2SLC22A12
SCHEMBL24617123 0.77 KIF11 (0.49) ARIMPDH2IMPDH1ESR2SLC22A12
SCHEMBL25543162 0.77 AR (0.41) ARIMPDH2IMPDH1ESR2SLC22A12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135516-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed