SCHEMBL23625541

SCHEMBL23625541

Cc1ccc(-c2ccc3cc(C#N)ccc3c2)c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.56
CYP11B2 P19099 2/20 0.56
CYP17A1 P05093 1/20 0.46
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
ABL1 P00519 1/20 0.41
CYP1A2 P05177 1/20 0.39
XDH P47989 1/20 0.39
SLC22A12 Q96S37 1/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
KCNH2 Q12809 1/20 0.37
CYP19A1 P11511 1/20 0.37
F2 P00734 1/20 0.37
PLG P00747 1/20 0.37
PLAU P00749 1/20 0.37
KLKB1 P03952 1/20 0.37
PRSS1 P07477 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
MCL1 Q07820 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20733779 0.84 CYP1A2 (0.48) CYP11B2CYP1A2SLC22A12AR
SCHEMBL23625538 0.83 ADRA2C (0.48) CYP1A2AR
SCHEMBL21389009 0.82 CYP1A2 (0.46) CYP11B2CYP1A2SLC22A12
SCHEMBL24617115 0.81 CYP11B1 (0.46) CYP11B1CYP11B2CYP17A1CA1CA2
SCHEMBL13192123 0.81 CYP11B1 (0.50) CYP11B1CYP11B2CYP17A1CA1CA2
SCHEMBL13170913 0.79 CYP11B1 (0.47) CYP11B1CYP11B2CYP17A1CA1CA2
SCHEMBL5746859 0.79 CYP1A2 (0.50) CYP1A2ESR1ESR2MCL1
SCHEMBL13192424 0.78 CYP11B1 (0.48) CYP11B1CYP11B2CYP17A1CA1CA2
SCHEMBL4311898 0.77 CYP11B1 (0.53) CYP11B1CYP11B2CYP17A1CA1CA2
SCHEMBL13171105 0.77 CYP11B1 (0.47) CYP11B1CYP11B2CYP17A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021135516-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT AND ELECTRONIC APPARATUS 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed