SCHEMBL21389009

SCHEMBL21389009

Cc1ccc(-c2ccc(-c3ccc(C#N)cc3)cc2)c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.46
KIF11 P52732 2/20 0.43
CYP11B2 P19099 3/20 0.42
MMP3 P08254 1/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP2A6 P11509 1/20 0.42
TSHR P16473 1/20 0.40
ATM Q13315 2/20 0.39
PDK2 Q15119 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDO2 P48775 1/20 0.39
TNKS O95271 1/20 0.39
EGLN2 Q96KS0 2/20 0.38
SLC22A12 Q96S37 1/20 0.38
HSD11B1 P28845 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20733779 0.98 CYP1A2 (0.48) CYP1A2KIF11CYP11B2MMP3ALDH1A1
SCHEMBL30451858 0.87 TSHR (0.52) KIF11CYP11B2MMP3ALDH1A1CYP2A6
SCHEMBL18322222 0.87 TSHR (0.52) KIF11CYP11B2MMP3ALDH1A1CYP2A6
SCHEMBL22049794 0.85 ALDH1A1 (0.61) KIF11CYP11B2MMP3ALDH1A1CYP2A6
SCHEMBL23625541 0.82 CYP11B1 (0.56) CYP1A2CYP11B2SLC22A12
SCHEMBL30708993 0.80 MAOA (0.48) CYP1A2KIF11CYP11B2MMP3TSHR
SCHEMBL26492407 0.80 GABRA1 (0.49) KIF11CYP11B2MMP3TSHRATM
SCHEMBL23655191 0.79 AR (0.49) KIF11CYP11B2MMP3ALDH1A1CYP2A6
SCHEMBL23625538 0.79 ADRA2C (0.48) CYP1A2ALDH1A1TSHRPDK2MEN1
SCHEMBL25708857 0.79 KIF11 (0.73) KIF11CYP11B2MMP3TSHRPDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019182402-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2019-09-26 WO disclosed
WO-2019182400-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2019-09-26 WO disclosed