Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA5 | P30532 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625641 | 0.92 | NPC1 (0.57) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL23625879 | 0.83 | NPC1 (0.71) | NPC1RAB9AMAPTPKMMMP9 | |
| SCHEMBL23625643 | 0.83 | NPC1 (0.61) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL23625872 | 0.83 | NPC1 (0.71) | NPC1KMT2ARAB9AMAPTPKM | |
| SCHEMBL15483234 | 0.81 | NPC1 (0.48) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL31051679 | 0.81 | NPC1 (0.51) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL8848782 | 0.80 | MMP9 (0.58) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL15481257 | 0.79 | NPC1 (0.49) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL18804644 | 0.74 | NPC1 (0.62) | NPC1KMT2AMEN1RAB9AMAPT | |
| SCHEMBL29736032 | 0.74 | NPC1 (0.77) | NPC1RAB9AMAPTPKMMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4085093-B1 | COMPOSITIONS FOR ELASTOMERIC COMPOUNDS INCLUDING POLYTETRAZOLE CROSS-LINKING AGENTS AND TYRES COMPRISING THE SAME | PIRELLI (IT) | 2023-11-08 | — | — | EP | disclosed |
| US-20230257552-A1 | COMPOSITIONS FOR ELASTOMERIC COMPOUNDS COMPRISING TETRAZOLE COMPATIBILIZING AGENTS AND TYRES COMPRISING THE SAME | PIRELLI TYRE S.P.A. (IT) | 2023-08-17 | — | — | US | disclosed |
| US-20230257552-A1 | COMPOSITIONS FOR ELASTOMERIC COMPOUNDS COMPRISING TETRAZOLE COMPATIBILIZING AGENTS AND TYRES COMPRISING THE SAME | PIRELLI TYRE S.P.A. (IT) | 2023-08-17 | — | — | US | disclosed |
| US-20230058851-A1 | COMPOSITIONS FOR ELASTOMERIC COMPOUNDS INCLUDING POLYTETRAZOLE CROSS-LINKING AGENTS AND TYRES COMPRISING THE SAME | PIRELLI TYRE S.P.A. (IT) | 2023-02-23 | — | — | US | disclosed |
| WO-2021260635-A1 | COMPOSITIONS FOR ELASTOMERIC COMPOUNDS COMPRISING TETRAZOLE COMPATIBILIZING AGENTS AND TYRES COMPRISING THE SAME | PIRELLI TYRE S.P.A. (IT) | 2021-12-30 | — | — | WO | disclosed |
| WO-2021137143-A1 | COMPOSITIONS FOR ELASTOMERIC COMPOUNDS INCLUDING POLYTETRAZOLE CROSS-LINKING AGENTS AND TYRES COMPRISING THE SAME | PIRELLI TYRE S.P.A. (IT) | 2021-07-08 | — | — | WO | disclosed |