Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22846538 | 0.78 | CCR1 (0.52) | MAPTKDM4EHTTCCR1CCR5 | |
| SCHEMBL24581695 | 0.78 | ALDH1A1 (0.41) | MAPTKDM4ECCR1CCR5CCR8 | |
| SCHEMBL25878168 | 0.75 | CLK1 (0.45) | CLK1DYRK1AMAPK10HIPK2TNF | |
| SCHEMBL25054661 | 0.75 | CLK1 (0.45) | CLK1DYRK1AMAPK10HIPK2TNF | |
| SCHEMBL18583892 | 0.73 | MAPT (0.40) | CLK1DYRK1AMAPK10MAPTKDM4E | |
| SCHEMBL1419171 | 0.72 | LMNA (0.58) | CLK1DYRK1AMAPK10MAPTTNF | |
| SCHEMBL29568934 | 0.72 | LMNA (0.58) | CLK1DYRK1AMAPK10MAPTTNF | |
| SCHEMBL17532798 | 0.72 | CLK1 (0.58) | CLK1DYRK1AMAPK10HIPK2TNF | |
| SCHEMBL672509 | 0.71 | CLK1 (0.54) | CLK1DYRK1AMAPK10HIPK2TNF | |
| SCHEMBL29569821 | 0.71 | CLK1 (0.54) | CLK1DYRK1AMAPK10HIPK2TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021135181-A1 | NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC DEVICE | 陕西莱特光电材料股份有限公司 | 2021-07-08 | — | — | WO | disclosed |