Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675377 | 0.80 | TDP1 (0.58) | TDP1GAAMEN1KMT2ACA1 | |
| SCHEMBL4616160 | 0.80 | MEN1 (0.41) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL34474705 | 0.79 | MEN1 (0.45) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL25859878 | 0.79 | MEN1 (0.45) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL17860156 | 0.78 | TDP1 (0.50) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL7518298 | 0.78 | TDP1 (0.50) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL31038364 | 0.77 | TDP1 (0.42) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL1222350 | 0.77 | TDP1 (0.49) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL1222348 | 0.77 | TDP1 (0.49) | TDP1GAAMEN1KMT2ASYK | |
| SCHEMBL4269209 | 0.77 | TDP1 (0.49) | TDP1GAAMEN1KMT2ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021136808-A1 | CONJUGATES UNDERGOING INTRAMOLECULAR REARRANGEMENTS | ASCENDIS PHARMA A/S (DK) | 2021-07-08 | — | — | WO | disclosed |