Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34474705 | 1.00 | MEN1 (0.45) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL17276466 | 0.84 | MEN1 (0.41) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL21995000 | 0.84 | MEN1 (0.45) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL21994998 | 0.84 | MEN1 (0.45) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL1105702 | 0.80 | PCSK9 (0.50) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL6563149 | 0.80 | MEN1 (0.50) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL25276798 | 0.79 | CTSS (0.38) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL25276799 | 0.79 | CTSS (0.38) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL25301268 | 0.79 | MEN1 (0.50) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL23626437 | 0.79 | TDP1 (0.49) | MEN1GAAKMT2ATDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134688-A1 | SALT OF ROCK INHIBITOR, CRYSTAL FORM OF SALT, COMPOSITION, AND PHARMACEUTICAL USE | 武汉朗来科技发展有限公司 | 2023-07-20 | — | — | WO | disclosed |