SCHEMBL1222348

SCHEMBL1222348

CC(C)(C)OC(=O)NCC(O)CO

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.49
MEN1 O00255 1/20 0.46
GAA P10253 1/20 0.46
KMT2A Q03164 1/20 0.46
CTSS P25774 5/20 0.42
CTSK P43235 5/20 0.42
CTSL P07711 1/20 0.42
CTSB P07858 1/20 0.42
SYK P43405 1/20 0.40
SERPINE1 P05121 1/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA7 P43166 1/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
CYP2D6 P10635 1/20 0.39
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
APLNR P35414 1/20 0.38
CA12 O43570 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3166361 1.00 TDP1 (0.49) TDP1MEN1GAAKMT2ACTSS
SCHEMBL1222350 1.00 TDP1 (0.49) TDP1MEN1GAAKMT2ACTSS
SCHEMBL570033 0.90 MEN1 (0.50) TDP1MEN1GAAKMT2ACTSS
SCHEMBL7755318 0.88 TDP1 (0.42) TDP1MEN1GAAKMT2ACTSS
SCHEMBL14721982 0.85 TDP1 (0.50) TDP1MEN1GAAKMT2ACTSS
SCHEMBL16379307 0.85 MEN1 (0.46) TDP1MEN1GAAKMT2ACTSS
SCHEMBL13960156 0.85 MEN1 (0.46) TDP1MEN1GAAKMT2ACTSS
SCHEMBL2369074 0.85 MEN1 (0.46) TDP1MEN1GAAKMT2ACTSS
SCHEMBL5352030 0.85 MEN1 (0.46) TDP1MEN1GAAKMT2ACTSS
SCHEMBL12880606 0.85 MEN1 (0.46) TDP1MEN1GAAKMT2ACTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 307 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388717-A1 POLYUREA ACRYLATE OLIGOMER CONTAINING PROTECTED GROUPS AND PREPARATION METHOD AND APPLICATION THEREOF UNIV ZHEJIANG (CN) 2025-12-25 US claimed
CN-118359515-A Betaine type zwitterionic lipid and preparation method thereof 大连理工大学 2024-07-19 CN claimed
CN-114181200-B Cationic liposome with efficient gene transfection efficiency and preparation and application thereof 华中科技大学 2023-09-29 CN claimed
CN-110302390-B Oxaliplatin precursor as phospholipid analogue, preparation method and application thereof 中国科学院上海药物研究所 2021-08-06 CN claimed
CN-110845724-B Polyamino acid, preparation method and application thereof 中国科学院长春应用化学研究所 2021-01-08 CN claimed
CN-110845724-A Polyamino acid, preparation method and application thereof 中国科学院长春应用化学研究所 2020-02-28 CN claimed
CN-110302390-A Class phosphatide oxaliplatin precursor, preparation method and the usage 中国科学院上海药物研究所 2019-10-08 CN claimed
CN-105669682-B A kind of intermediate of DPP-IV inhibitor 成都先导药物开发股份有限公司 2019-08-30 CN claimed
CN-104448815-B A kind of thermoplastic resin composition and preparation method thereof 上海金发科技发展有限公司 2018-02-16 CN claimed
CN-105669682-A Intermediates of DPP-IV inhibitor 成都先导药物开发有限公司 2016-06-15 CN claimed
EP-4743440-A1 IONIZABLE LIPIDS eTheRNA immunotherapies NV (BE) 2026-05-20 EP disclosed
EP-4735439-A1 KRAS INHIBITORS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
EP-4735440-A1 KRAS INHIBITORS Bristol-Myers Squibb Company (US) 2026-05-06 EP disclosed
US-12617802-B2 Sulfonimidamide compounds as NLRP3 modulators GENENTECH, INC. (US) 2026-05-05 US disclosed
WO-2026087635-A1 DIHYDRO BENZOXAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2026-04-30 WO disclosed
WO-1994025477-A2 NOVEL PEPTIDE NUCLEIC ACIDS NIELSEN PETER E (DK) 1994-11-10 WO disclosed
EP-0586618-A1 THE USE OF NUCLEIC ACID ANALOGUES IN DIAGNOSTICS AND ANALYTICAL PROCEDURES. BUCHARDT OLE (DK) 1994-03-16 EP disclosed
EP-0586474-A1 PEPTIDE NUCLEIC ACIDS BUCHARDT, Ole (DK) 1994-03-16 EP disclosed
WO-1992020702-A1 PEPTIDE NUCLEIC ACIDS BUCHARDT OLE (DK) 1992-11-26 WO disclosed
WO-1992020703-A1 THE USE OF NUCLEIC ACID ANALOGUES IN DIAGNOSTICS AND ANALYTICAL PROCEDURES BUCHARDT OLE (DK) 1992-11-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617802-B2 Sulfonimidamide compounds as NLRP3 modulators NLRP3, NLRP1, PYCARD TDP1 2524/4885MEN1 4299/4885GAA 4667/4885
US-20250388717-A1 POLYUREA ACRYLATE OLIGOMER CONTAINING PROTECTED GROUPS AND PREPARATION METHOD AND APPLICATION THEREOF DCTD, UMPS, IMPDH1 TDP1 29/4885MEN1 3297/4885GAA 3631/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.