SCHEMBL23626438

SCHEMBL23626438

c1ccc(-c2ccc(N(c3cccc(-c4cc5ccccc5c5ccccc45)c3)c3ccc4sc5ccccc5c4c3)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.35
ALOX5 P09917 1/20 0.34
GPR3 P46089 1/20 0.33
PIM3 Q86V86 1/20 0.32
APP P05067 1/20 0.32
ALDH1A1 P00352 3/20 0.32
HPGD P15428 3/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
MPI P34949 1/20 0.32
KMT2A Q03164 1/20 0.32
GPR84 Q9NQS5 2/20 0.32
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
CASP1 P29466 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23822488 0.96 CYP11B1 (0.35) CYP11B1ALOX5GPR3PIM3APP
SCHEMBL25463845 0.95 CYP11B1 (0.35) CYP11B1ALOX5GPR3PIM3ALDH1A1
SCHEMBL25463819 0.94 CYP11B1 (0.35) CYP11B1ALOX5GPR3PIM3ALDH1A1
SCHEMBL23822178 0.94 CYP11B1 (0.38) CYP11B1ALOX5GPR3PIM3ALDH1A1
SCHEMBL23822487 0.94 CYP11B1 (0.38) CYP11B1ALOX5GPR3PIM3ALDH1A1
SCHEMBL24839184 0.93 S1PR5 (0.34) CYP11B1ALOX5GPR3PIM3ALDH1A1
SCHEMBL26020344 0.93 CYP11B1 (0.34) CYP11B1APPALDH1A1HPGDMAPT
SCHEMBL22077925 0.93 CYP11B1 (0.35) CYP11B1GPR3PIM3ALDH1A1HPGD
SCHEMBL23626493 0.93 ALDH1A1 (0.35) CYP11B1ALOX5GPR3PIM3APP
SCHEMBL16837500 0.93 CYP11B1 (0.35) CYP11B1ALOX5GPR3PIM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240237511-A1 PLURALITY OF ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-07-11 US disclosed
US-20240237511-A1 PLURALITY OF ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-07-11 US disclosed
US-20210351358-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2021-11-11 US disclosed
US-20210210684-A1 PLURALITY OF ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2021-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210210684-A1 PLURALITY OF ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, PIEZO1, ODC1 CYP11B1 3728/4885ALOX5 1138/4885GPR3 4586/4885
US-20240237511-A1 PLURALITY OF ORGANIC ELECTROLUMINESCENT MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME L1CAM, ODC1, PIEZO1 CYP11B1 3662/4885ALOX5 1033/4885GPR3 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.