Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364379 | 0.96 | NPC1 (0.32) | KDM4EPOLBMAPTKMT2ANPC1 | |
| SCHEMBL2364461 | 0.91 | NPC1 (0.32) | NPC1PKM | |
| SCHEMBL2362904 | 0.83 | NPC1 (0.31) | NPC1PKM | |
| SCHEMBL2362818 | 0.78 | POLB (0.34) | KDM4EPOLBMAPTKMT2ANPC1 | |
| SCHEMBL3134190 | 0.77 | NPC1 (0.32) | NPC1PKM | |
| SCHEMBL18241095 | 0.76 | PKM (0.33) | NPC1PKM | |
| SCHEMBL2362709 | 0.74 | PKM (0.35) | KMT2ANPC1PKM | |
| SCHEMBL2362832 | 0.74 | NPC1 (0.32) | NPC1PKM | |
| SCHEMBL15768037 | 0.73 | KDM4E (0.39) | KDM4EMAPTKMT2A | |
| SCHEMBL2364378 | 0.73 | POLB (0.35) | KDM4EPOLBMAPTNPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2352723-A2 | HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |