Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364379 | 0.93 | NPC1 (0.32) | NPC1PKM | |
| SCHEMBL2362819 | 0.91 | KDM4E (0.35) | NPC1PKM | |
| SCHEMBL2362904 | 0.85 | NPC1 (0.31) | NPC1PKM | |
| SCHEMBL18241095 | 0.84 | PKM (0.33) | NPC1PKML3MBTL1 | |
| SCHEMBL2362832 | 0.82 | NPC1 (0.32) | NPC1PKML3MBTL1 | |
| SCHEMBL2362709 | 0.82 | PKM (0.35) | NPC1PKML3MBTL1 | |
| SCHEMBL12612226 | 0.79 | NPC1 (0.31) | NPC1PKM | |
| SCHEMBL3134190 | 0.79 | NPC1 (0.32) | NPC1PKML3MBTL1 | |
| SCHEMBL12611761 | 0.78 | PKM (0.42) | NPC1PKM | |
| SCHEMBL2364460 | 0.76 | MAPT (0.36) | NPC1PKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-2352723-A2 | HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010133312-A1 | HALOGEN-SUBSTITUTED COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-11-25 | — | — | WO | disclosed |
| EP-2253617-A1 | Halogenated compounds as pesticides | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |