Ether

Ether

SCHEMBL2362844

C1CCC1.C=CC(=O)Oc1ccccc1.CCOCC.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.48
THRA P10827 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MAPT P10636 2/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.37
ALDH1A1 P00352 3/20 0.37
RAB9A P51151 1/20 0.37
PDE6D O43924 1/20 0.37
ELANE P08246 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TGM2 P21980 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL37233 0.95 THRB (0.51) THRBTHRAMAPTZDHHC2ALDH1A1
Ether SCHEMBL2818434 0.94 THRB (0.50) THRBTHRAMAPTZDHHC2ALDH1A1
Ether SCHEMBL6578176 0.94 THRB (0.50) THRBTHRAMAPTZDHHC2ALDH1A1
Ether SCHEMBL1246730 0.91 THRB (0.56) THRBTHRAMAPTZDHHC2ALDH1A1
1,6-Hexanediol SCHEMBL23069547 0.89 THRB (0.46) THRBTHRAMAPTZDHHC2ALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL2345984 0.88 THRB (0.48) THRBTHRAMAPTZDHHC2ALDH1A1
Triethylene Glycol SCHEMBL7896473 0.87 THRB (0.47) THRBTHRAKDM4EMAPTZDHHC2
Tetraethylene Glycol SCHEMBL18092769 0.87 THRB (0.47) THRBTHRAKDM4EMAPTZDHHC2
Ethylene Glycol SCHEMBL2694080 0.86 THRB (0.56) THRBTHRAKDM4EALDH1A1PDE6D
Diethylene Glycol Monoethyl Ether SCHEMBL1508669 0.84 THRB (0.47) THRBTHRAMAPTZDHHC2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8735004-B2 Overcharge inhibitor, and nonaqueous electrolyte solution and secondary battery using the same HITACHI, LTD. (JP) 2014-05-27 US disclosed
EP-2355228-A1 Overcharge inhibitor, and nonaqueous electrolyte solution and secondary battery using the same Hitachi Ltd. (JP) 2011-08-10 EP disclosed
US-20110189550-A1 OVERCHARGE INHIBITOR, AND NONAQUEOUS ELECTROLYTE SOLUTION AND SECONDARY BATTERY USING THE SAME HITACHI, LTD. 2011-08-04 US disclosed