Ether

Ether

SCHEMBL6578176

C=C.C=CC(=O)Oc1ccccc1.CCOCC.OCCO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 5/20 0.50
THRA P10827 1/20 0.43
MAPT P10636 2/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
PDE6D O43924 1/20 0.38
ELANE P08246 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TGM2 P21980 1/20 0.36
ALDH1A1 P00352 3/20 0.35
LMNA P02545 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR1A P08908 1/20 0.35
RECQL P46063 1/20 0.34
AKT1 P31749 1/20 0.34
TSHR P16473 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ether SCHEMBL2818434 1.00 THRB (0.50) THRBTHRAMAPTZDHHC2PDE6D
Ether SCHEMBL37233 0.98 THRB (0.51) THRBTHRAMAPTZDHHC2PDE6D
1,6-Hexanediol SCHEMBL23069547 0.94 THRB (0.46) THRBTHRAMAPTZDHHC2PDE6D
Ether SCHEMBL2362844 0.94 THRB (0.48) THRBTHRAMAPTZDHHC2PDE6D
Ether SCHEMBL1246730 0.94 THRB (0.56) THRBTHRAMAPTZDHHC2PDE6D
Di(Hydroxyethyl)Ether SCHEMBL2345984 0.91 THRB (0.48) THRBTHRAMAPTZDHHC2PDE6D
Triethylene Glycol SCHEMBL7896473 0.90 THRB (0.47) THRBTHRAMAPTZDHHC2PDE6D
Tetraethylene Glycol SCHEMBL18092769 0.90 THRB (0.47) THRBTHRAMAPTZDHHC2PDE6D
Ethylene Glycol SCHEMBL2694080 0.88 THRB (0.56) THRBTHRAPDE6DSMN1; SMN2TGM2
Diethylene Glycol Monoethyl Ether SCHEMBL1508669 0.87 THRB (0.47) THRBTHRAMAPTZDHHC2PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1088866-B1 Inks containing glycol ethers and specific polymers for dry time and bleed improvements in ink-jet printing inks HEWLETT PACKARD CO (US) 2004-04-28 EP claimed