Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18797115 | 0.74 | CDK8 (0.35) | CDK8ACVR1 | |
| SCHEMBL18797108 | 0.66 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL8404364 | 0.59 | MAPT (0.44) | — | |
| SCHEMBL14101723 | 0.59 | GPR139 (0.43) | — | |
| SCHEMBL13346995 | 0.58 | GAA (0.38) | — | |
| SCHEMBL18876006 | 0.57 | CYP2A6 (0.42) | — | |
| SCHEMBL21505452 | 0.57 | MAPT (0.42) | — | |
| SCHEMBL22025566 | 0.57 | MAPT (0.42) | — | |
| SCHEMBL14113158 | 0.57 | MAPT (0.42) | — | |
| SCHEMBL30640462 | 0.57 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368523-B1 | NOVEL PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-07-14 | — | — | EP | claimed |