Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15867195 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10ELANE | |
| SCHEMBL23628555 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10ELANE | |
| SCHEMBL2761277 | 0.87 | ELANE (0.49) | KDM4EALDH1A1HPGDHSD17B10ELANE | |
| SCHEMBL31410748 | 0.85 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDHSD17B10AR | |
| SCHEMBL29575324 | 0.80 | ELANE (0.38) | ALDH1A1ELANEARMEN1KMT2A | |
| SCHEMBL15867197 | 0.80 | ELANE (0.38) | ALDH1A1ELANEARMEN1KMT2A | |
| SCHEMBL27281232 | 0.79 | ELANE (0.42) | KDM4EALDH1A1HPGDHSD17B10ELANE | |
| SCHEMBL18089663 | 0.79 | NR1H2 (0.38) | ELANEADRA1AADRA1B | |
| SCHEMBL4352323 | 0.78 | MEN1 (0.46) | KDM4EALDH1A1HPGDHSD17B10AR | |
| SCHEMBL7789873 | 0.78 | ADRA1A (0.39) | ALDH1A1HSD17B10ARMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11649222-B2 | Compounds | UNIVERSITETET I OSLO (NO) | 2023-05-16 | — | — | US | disclosed |
| EP-3978488-A1 | ZINC CHELATING COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION | Universitetet I Oslo (NO) | 2022-04-06 | — | — | EP | disclosed |
| CN-109952297-B | Compound (I) | 奥斯陆大学 | 2022-02-25 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11649222-B2 | Compounds | SLC30A6, SLC39A11, SLC39A3 | KDM4E 2941/4885ALDH1A1 3235/4885HPGD 448/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.